CENTOGENE & ACTICO

How decision management technology enables fast, high-quality automation of data curation workflows

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Healthcare and Life Science | Advanced Decision Automation | Americas and Europe

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The automation we have implemented ultimately helps us deliver better, faster diagnoses. This is possible because the curation process that used to take a month now takes five minutes. It’s dramatic proof of how the ACTICO platform gives us the confidence to apply a similar approach to other processes in the future. Everyone trusts it.

Prof. Dr. Carsten Ullrich

Director of Artificial Intelligence, CENTOGENE

Outlook

Business & Patient Value

This case study provides dramatic proof of how the ACTICO Decision Management Platform can deliver significant business value by using a rules-based decision-making engine to automate data curation. In this instance, the business value is enhanced by the benefit to patients of faster, more accurate and continuously updated rare disease diagnosis. Looking to the future, CENTOGENE is keen to replicate their success by applying the same approach to automate other essential processes. Moreover, CENTOGENE is actively exploring how to extend their use of the ACTICO Decision Management Platform to include, for example, the Machine Learning module.

Challenge

Rare disease diagnoses in minutes, not weeks

For patients who are suffering from an undiagnosed rare genetic disease, receiving a diagnosis as early as possible is vital. As a world leader in genetic diagnostics for rare diseases, Rostock-founded CENTOGENE GmbH is committed to accelerating the diagnosis of these conditions. The company’s partnership with Business Rules specialists S&D, and the implementation of the ACTICO Decision Management Platform, has enabled them to succeed in this aim. How? By automating and optimizing the labor intensive diagnostic data curation process.

 

Reduce Patient Suffering
  • Diagnosing rare diseases can be a slow and painstaking process, resulting in unnecessary patient suffering.
  • Therefore, CENTOGENE wanted to accelerate the curation of key diagnostic data by integrating artificial intelligence into the relevant workflow.

Solution

Automation of the Data Curation Process

  • ACTICO Business Rules Engine, implemented in partnership with Business Rules specialists S&D
  • Integration of decision-making automation into the curation workflow, with increasing levels of automation until all manual processing tasks were eliminated.

Impact

Accelerated Diagnosis – ACTICO Decision Management Platform in use at CENTOGENE

  • Data curation process fully automated.
  • Data results delivery reduced from one month, to just five minutes.
  • More time for scientists to spend investigating the most difficult cases.

 

“We are now able to batch the processing of thousands of patient samples with this fully integrated solution and save up to one month of work for every case.”
ACTICO client centogene

About our customer

CENTOGENE engages in diagnosis and research around rare diseases transforming real-world clinical and genetic data into actionable information for patients, physicians, and pharmaceutical companies. Our goal is to bring rationality to treatment decisions and to accelerate the development of new orphan drugs by using our extensive rare disease knowledge, including epidemiological and clinical data, as well as innovative
biomarkers. CENTOGENE has developed a global proprietary rare disease platform based on our realworld data repository with over 3.6 billion weighted data points from approximately 570,000 patients representing over 120 different countries as of August 31, 2020.

Contact

Questions about our Intelligent Decision Automation Solutions?
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